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1

Drug-induced lupus erythematosus

He, Ye, Sawalha, Amr H.

Journal:

Current Opinion in Rheumatology

Year:

2018

Language:

english

File:

PDF, 441 KB

english, 2018

2

Novel Associations for Hypothyroidism Include Known Autoimmune Risk Loci

Eriksson, Nicholas, Tung, Joyce Y., Kiefer, Amy K., Hinds, David A., Francke, Uta, Mountain, Joanna L., Do, Chuong B., Sawalha, Amr H.

Journal:

Year:

2012

Language:

english

File:

PDF, 750 KB

english, 2012

3

Microorganisms in the human placenta are associated with altered CpG methylation of immune and inflammation-related genes

Tomlinson, Martha Scott, Bommarito, Paige A., Martin, Elizabeth M., Smeester, Lisa, Fichorova, Raina N., Onderdonk, Andrew B., Kuban, Karl C. K., O’Shea, T. Michael, Fry, Rebecca C., Sawalha, Amr H

Journal:

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

4

Noodling and Mycobacterium marinum infection mimicking seronegative rheumatoid arthritis complicated by anti–tumor necrosis factor α therapy

Aikaterini Thanou-Stavraki, Amr H. Sawalha, A. Neil Crowson, John B. Harley

Journal:

Arthritis Care & Research

Year:

2011

Language:

english

File:

PDF, 257 KB

english, 2011

5

MEK/ERK pathway inhibitors as a treatment for inflammatory arthritis might result in the development of lupus: Comment on the article by Thiel et al

Amr H. Sawalha, Bruce Richardson

Journal:

Arthritis & Rheumatism

Year:

2008

Language:

english

File:

PDF, 40 KB

english, 2008

6

A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease

Amr H. Sawalha, Travis Hughes, Ajay Nadig, Vuslat Yılmaz, Kenan Aksu, Gokhan Keser, Ayse Cefle, Ayten Yazıcı, Andaç Ergen, Marta E. Alarcón-Riquelme, Carlo Salvarani, Bruno Casali, Haner Direskeneli,

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 121 KB

english, 2011

7

Defective DNA methylation and CD70 overexpression in CD4+ T cells in MRL/lpr lupus-prone mice

Amr H. Sawalha, Matlock Jeffries

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 254 KB

english, 2007

8

The genetics of primary Sjögren’s syndrome

Amr H. Sawalha, Robyn Potts, Wendi R. Schmid, R. Hal Scofield, John B. Harley

Journal:

Current Rheumatology Reports

Year:

2003

Language:

english

File:

PDF, 565 KB

english, 2003

9

Dehydroepiandrosterone in systemic lupus erythematosus

Amr H. Sawalha, Susan Kovats

Journal:

Current Rheumatology Reports

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

10

Horizons in Sjögren’s Syndrome Genetics

Pamela H. Williams, Beth L. Cobb, Bahram Namjou, R. Hal Scofield, Amr H. Sawalha, John B. Harley

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2007

Language:

english

File:

PDF, 198 KB

english, 2007

11

Genetic Association of IL-21 Polymorphisms with Systemic Lupus Erythematosus

Amr H. Sawalha, Kenneth Kaufman, Jennifer Kelly, Teresa Aberle, Adam Adler, Jeff Kilpatrick, Edward Wakeland, Quan-Zhen Li, Amy Wandstrat, Judith James, Joan Merrill, Peter Lipsky, John B. Harley

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

12

The Presence of Anti-La Autoantibody is Associated with a Lower Risk of Nephritis and Seizures in Lupus Patients

Sanober Malik, Gail R. Bruner, Lourdes Feo, Courtney Williams-Weese, R. Hal Scofield, John B. Harley, Amr H. Sawalha

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

13

Sa.1. Defective T Cell ERK Signaling Induces Interferon-regulated Gene Expression and Overexpression of Methylation Sensitive Genes Similar to Lupus Patients

Amr Sawalha, Matlock Jeffries, Ryan Webb, Qianjin Lu, Gabriela Gorelik, Donna Ray, Kent Johnson, Bruce Richardson

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 116 KB

english, 2008

14

Sa.3. Overexpression of Human CD40L Activates Autologous B Cells and Increases Plasma Cell Differentiation in vitro in the Absence of Antigen Presentation

Yujun Pan, Yiping Fei, Amr Sawalha

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

15

Sa.9. Common Variants within MECP2 Confer Risk of Systemic Lupus Erythematosus

Amr Sawalha, Ryan Webb, Shizhong Han, Jennifer Kelly, Kenneth Kaufman, Robert Kimberly, Marta Alarcón-Riquelme, Judith James, Timothy Vyse, Gary Gilkeson, Chan-Bum Choi, Hal Scofield, Sang-Cheol Bae,

Journal:

Clinical Immunology

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

16

T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus

Ying Zhou, Jun Yuan, Yujun Pan, Yiping Fei, Xiangning Qiu, Nan Hu, Yongqi Luo, Wenzhi Lei, Yaping Li, Hai Long, Amr H Sawalha, Bruce Richardson, Qianjin Lu

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 1011 KB

english, 2009

17

Autoimmunity and Klinefelter's syndrome: When men have two X chromosomes

Amr H. Sawalha, John B. Harley, R. Hal Scofield

Journal:

Journal of Autoimmunity

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

18

Environmental exposure, estrogen and two X chromosomes are required for disease development in an epigenetic model of lupus

Faith M. Strickland, Anura Hewagama, Qianjian Lu, Ailing Wu, Robert Hinderer, Ryan Webb, Kent Johnson, Amr H. Sawalha, Colin Delaney, Raymond Yung, Bruce C. Richardson

Journal:

Journal of Autoimmunity

Year:

2012

Language:

english

File:

PDF, 933 KB

english, 2012

19

Sex-specific differences in the relationship between genetic susceptibility, T cell DNA demethylation and lupus flare severity

Amr H. Sawalha, Lu Wang, Ajay Nadig, Emily C. Somers, W. Joseph McCune, Travis Hughes, Joan T. Merrill, R. Hal Scofield, Faith M. Strickland, Bruce Richardson

Journal:

Journal of Autoimmunity

Year:

2012

Language:

english

File:

PDF, 490 KB

english, 2012

20

Epigenetics in systemic lupus erythematosus: leading the way for specific therapeutic agents

Jeffries, Matlock A, Sawalha, Amr H

Journal:

International Journal of Clinical Rheumatology

Year:

2011

Language:

english

File:

PDF, 394 KB

english, 2011

21

Aberrant DNA methylation in skin diseases

Li, Yaping, Sawalha, Amr H., Lu, Qianjin

Journal:

Journal of Dermatological Science

Year:

2009

Language:

english

File:

PDF, 247 KB

english, 2009

22

Epigenetic regulation and the pathogenesis of systemic lupus erythematosus

Yujun Pan, Amr H. Sawalha

Journal:

Translational Research

Year:

2009

Language:

english

File:

PDF, 121 KB

english, 2009

23

Impaired DNA methylation and its mechanisms in CD4+T cells of systemic lupus erythematosus

Zhang, Yiqun, Zhao, Ming, Sawalha, Amr H., Richardson, Bruce, Lu, Qianjin

Journal:

Journal of Autoimmunity

Year:

2013

Language:

english

File:

PDF, 337 KB

english, 2013

24

Epigenetics and T-cell immunity

Journal:

Year:

2008

Language:

english

File:

PDF, 196 KB

english, 2008

25

Diet Influences Expression of Autoimmune-Associated Genes and Disease Severity by Epigenetic Mechanisms in a Transgenic Mouse Model of Lupus

Strickland, Faith M., Hewagama, Anura, Wu, Ailing, Sawalha, Amr H., Delaney, Colin, Hoeltzel, Mark F., Yung, Raymond, Johnson, Kent, Mickelson, Barbara, Richardson, Bruce C.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 1.59 MB

english, 2013

26

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

Coit, Patrick, Jeffries, Matlock, Altorok, Nezam, Dozmorov, Mikhail G., Koelsch, Kristi A., Wren, Jonathan D., Merrill, Joan T., McCune, W. Joseph, Sawalha, Amr H.

Journal:

Journal of Autoimmunity

Year:

2013

Language:

english

File:

PDF, 889 KB

english, 2013

27

Current status of lupus genetics

Andrea L Sestak, Swapan K Nath, Amr H Sawalha…

Journal:

Arthritis Research & Therapy

Year:

2007

Language:

english

File:

PDF, 88 KB

english, 2007

28

Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse

Koelsch, Kristi A., Webb, Ryan, Jeffries, Matlock, Dozmorov, Mikhail G., Frank, Mark Barton, Guthridge, Joel M., James, Judith A., Wren, Jonathan D., Sawalha, Amr H.

Journal:

Journal of Autoimmunity

Year:

2013

Language:

english

File:

PDF, 668 KB

english, 2013

29

Epigenetics in the treatment of systemic lupus erythematosus: Potential clinical application

Guo, Yu, Sawalha, Amr H., Lu, Qianjin

Journal:

Clinical Immunology

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

30

Epigenome-Wide Scan Identifies a Treatment-Responsive Pattern of Altered DNA Methylation Among Cytoskeletal Remodeling Genes in Monocytes and CD4+ T Cells From Patients With Behçet's Disease

Hughes, Travis, Ture-Ozdemir, Filiz, Alibaz-Oner, Fatma, Coit, Patrick, Direskeneli, Haner, Sawalha, Amr H.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 385 KB

english, 2014

31

Genome-Wide DNA Methylation Patterns in Naive CD4+ T Cells From Patients With Primary Sjögren's Syndrome

Altorok, Nezam, Coit, Patrick, Hughes, Travis, Koelsch, Kristi A., Stone, Donald U., Rasmussen, Astrid, Radfar, Lida, Scofield, R. Hal, Sivils, Kathy L., Farris, A. Darise, Sawalha, Amr H.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 163 KB

english, 2014

32

The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus

Travis Hughes,Amr H Sawalha

Journal:

Arthritis Research & Therapy

Year:

2011

Language:

english

File:

PDF, 1.82 MB

english, 2011

33

The DNA methylation signature of human TCRαβ+CD4−CD8− double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response

Renauer, Paul A., Coit, Patrick, Sawalha, Amr H.

Journal:

Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

34

Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage

Jeffries, Matlock A., Donica, Madison, Baker, Lyle W., Stevenson, Michael E., Annan, Anand C., Humphrey, Mary Beth, James, Judith A., Sawalha, Amr H.

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 573 KB

english, 2014

35

Step by Step

Sawalha, Amr H., Bronze, Michael S., Saint, Sanjay, Blevins, Steve, Kern, William

Journal:

Boston Medical and Surgical Journal

Year:

2003

Language:

english

File:

PDF, 145 KB

english, 2003

36

Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?

Jeffries, Matlock A, Sawalha, Amr H

Journal:

Expert Review of Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 545 KB

english, 2015

37

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

Coit, Patrick, Yalavarthi, Srilakshmi, Ognenovski, Mikhail, Zhao, Wenpu, Hasni, Sarfaraz, Wren, Jonathan D., Kaplan, Mariana J., Sawalha, Amr H.

Journal:

Journal of Autoimmunity

Year:

2015

Language:

english

File:

PDF, 1.08 MB

english, 2015

38

Epigenetics in the pathogenesis of systemic lupus erythematosus

Altorok, Nezam, Sawalha, Amr H.

Journal:

Current Opinion in Rheumatology

Year:

2013

Language:

english

File:

PDF, 221 KB

english, 2013

39

Protein Kinase Cδ Mutations May Contribute to Lupus Through Effects on T Cells: Comment on the Article by Belot et al

Richardson, Bruce, Strickland, Faith M., Sawalha, Amr H., Gorelik, Gabriela

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 111 KB

english, 2014

40

T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice

Gorelik, Gabriela, Sawalha, Amr H., Patel, Dipak, Johnson, Kent, Richardson, Bruce

Journal:

Clinical Immunology

Year:

2015

Language:

english

File:

PDF, 1.11 MB

english, 2015

41

Still Consider the Source

Sawalha, Amr H., Saint, Sanjay, Ike, Robert W., Bronze, Michael S.

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

42

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

Altorok, Nezam, Tsou, Pei-Suen, Coit, Patrick, Khanna, Dinesh, Sawalha, Amr H

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 994 KB

english, 2015

43

Epigenetics and Vasculitis: a Comprehensive Review

Renauer, Paul, Coit, Patrick, Sawalha, Amr H.

Journal:

Clinical Reviews in Allergy & Immunology

Year:

2016

Language:

english

File:

PDF, 644 KB

english, 2016

44

DNA Methylation in the Pathogenesis of Systemic Lupus Erythematosus

Sawalha, Amr, Richardson, Bruce

Journal:

Current Pharmacogenomics

Year:

2005

Language:

english

File:

PDF, 49 KB

english, 2005

45

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells

Coit, Patrick, Renauer, Paul, Jeffries, Matlock A., Merrill, Joan T., McCune, W. Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H.

Journal:

Journal of Autoimmunity

Year:

2015

Language:

english

File:

PDF, 437 KB

english, 2015

46

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus

Renauer, Paul, Coit, Patrick, Jeffries, Matlock A, Merrill, Joan T, McCune, W Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H

Journal:

Lupus Science & Medicine

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

47

Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival

Kazzaz, Nayef M, Coit, Patrick, Lewis, Emily E, McCune, W Joseph, Sawalha, Amr H, Knight, Jason S

Journal:

Lupus Science & Medicine

Year:

2015

Language:

english

File:

PDF, 1.27 MB

english, 2015

48

Uric Acid Directly Promotes Human T-Cell Activation

Webb, Ryan, Jeffries, Matlock, Sawalha, Amr H.

Journal:

The American Journal of the Medical Sciences

Year:

2009

Language:

english

File:

PDF, 466 KB

english, 2009

49

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus

Jeffries, Matlock, Dozmorov, Mikhail, Tang, Yuhong, Merrill, Joan T., Wren, Jonathan D., Sawalha, Amr H.

Journal:

Year:

2011

Language:

english

File:

PDF, 2.50 MB

english, 2011

50

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity

Coit, Patrick, Ognenovski, Mikhail, Gensterblum, Elizabeth, Maksimowicz-McKinnon, Kathleen, Wren, Jonathan D., Sawalha, Amr H.

Journal:

Epigenetics & Chromatin

Year:

2015

Language:

english

File:

PDF, 4.04 MB

english, 2015